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Original Article
Nonoperative Treatment of PDA Using the Duct-OccludⓇ
Dong Woon Shin, Kyung Hee Lee, Heon-Seok Han
Clin Exp Pediatr. 1997;40(5):635-640.   Published online May 15, 1997
Purpose : Among the several transcatheter devices of PDA occlusion, Rashikind device was the most extensively experienced, but it had risk of occluder embolism and incomplete occlusion of PDA, approximately 27%. The authors used Duct-OccludⓇ, made of 0.028 inch stainless steel coil. The coil is double cone-shape in released state, and used in streched condition through 4F implantation catheter for...
Prophylactic Treatment of Anemia of Prematurity with Recombinant Human Erythropoietin and High Doses of Iron
Young Ho Lee, Ahn Hong Choi, Soon Yong Lee, Jeong Sook Park, Bong Keun Choi, Hyoung Shim Chang
Clin Exp Pediatr. 1997;40(3):361-367.   Published online March 15, 1997
Purpose : We conducted randomized study to determine whether high doses(6mg/kg/ day) of iron would exert a more supplemental effect than low doses(3mg/kg/day), and which regimen of recombinant human erythropoietin(rHuEPO) and iron would be more beneficial in the prophylactic treatment of anemia of prematurity. Methods : We randomly assigned 38 sick premature infants who were more likely than symptom-free premature infants requiring erythrocyte transfusions for...
Effect of Indomethacin Therapy in Prematurity with Patent Ductus Arteriosus:study of Its Effectiveness in Treatment Modality
Yun Kyeong Bae, Seong Woo Roh, Min Jeong Kim, Son Sang Seo
Clin Exp Pediatr. 1996;39(9):1239-1246.   Published online September 15, 1996
Purpose : Conventional indomethacin therapy(0.2mg/kg every 12 hours for three doses) has been used for closure of PDA. The effect of prolonged low dose of indomethacin therapy(0.1mg/kg daily for six days)had been reported in foreign country but, nothing had been reported in our country. So we attempted this study to examine effects of these two methods. Methods : Forty one infants with PDA of...
The Effect of Recombinant Human Growth Hormone on the Growth in the Children with Chronic Renal Failure
Sei Won Yang, Young Choi
Clin Exp Pediatr. 1996;39(7):997-1004.   Published online July 15, 1996
Purpose : We observed the effect of three year-administration of recombinant human growth hormone(rhGH) on the growth in the children with chronic renal failure(CRF). Methods : Five prepubertal children(three boys and two girls) with CRF, who had been managed by conservative methods, were given rhGH(1 U/kg/week) for three years. Growth parameters, such as growth velocity, height standard deviation score(SDS), and predicted final adult height, obtained...
The Concentration of Insulin Like Growth Factor-I(IGF-I) and IGF-Binding Protein-3 (IGFBP-3) in the Serum of Children with Growth Hormone Deficiency and the Alterations after Growth Hormone Treatment
Woo Yeong Chung, Dae-Yeol Lee
Clin Exp Pediatr. 1996;39(6):846-855.   Published online June 15, 1996
Purpose : The insulin like growth factors (IGFs) circulate complexed to IGF-binding proteins(IGFBPs). IGFBP-3 is the major circulating IGFBP and is found primarily as a 150 kDa complex which contains an acid labile subunit(ALS), IGFBP-3, and IGF-I or IGF-II and is considered to be growth hormone(GH) dependent. In this study, we measured serum IGF-I, IGFBP-3 and 150 kDa levels in sera of growth hormone...
Prospective, Controlled Trial with Dipheny1-dimethy1-dicarboxylate in Children with Chronic Liver Diseses : The Effect on Lowering Serum Aminotransferase Levels
Ji Eun Wunon, Sang Gil An, Ki Moon Cha, Yong Min Chung, Hee Sup Kim, Hann Tchah, Ho Jin Park
Clin Exp Pediatr. 1995;38(10):1378-1383.   Published online October 15, 1995
Purpose : The prospective cotrolled study was performed to identify the effect of the dipheny1-dimethy1-dicarboxylate(PMC) on lowering serum transaminases in children with chronic liver diseases. Methods : The twenty patients were paticipated in this study who were followed up in the Department of Pediatrics of the Seoul Red Cross Hospital because of the elevated levels of serum alaine aminotransferase(ALT) and aspartate...
Clinical and Histologic Changes in Children with Chronic Hepatitis B Virus Infection after Alpha Interferon Therapy
Kyung Mo Kim, Soo Jong Hong, Young Seo Park, Hyung Nam Moon, Chang Yee Hong, Joo Ryoung Huh
Clin Exp Pediatr. 1995;38(9):1232-1241.   Published online September 15, 1995
Purpose : Several trials in children for chronic hepatitis B have shown the efficacy of alpha interferon in eliminating hepatitis B virus replication, accompanied by an improvement in the liver cell damage. But reports about the alpha interferon therapy are rare in Korean children and there is no report about histologic changes even with adult. So we tried to...
A Clinical Study on Chronic Hepatitis b in the Children
Bon Su Koo, Han Sang Joo, Yung Tak Lim, Hee Ju Park
Clin Exp Pediatr. 1994;37(6):767-775.   Published online June 15, 1994
The author observed clinical study and response of -interferon treatment of 43 cases of chronic hepatitis who were admitted to Department of Pediatrics Pusan National University College of Medicine during the period of 4 year 6 months from Jenuary, 1988 to Jun, 1992. The results were as follows: 1) Of 43 patients with chronic hepatitis CPH was 17 cases (39.5%) and CAH...
The Effect of Long-Term Corticosteroid Treatment on Height Velocity in Childhood
Byung Mun Lee, Chan Yung Kim
Clin Exp Pediatr. 1993;36(2):185-194.   Published online February 15, 1993
The auther analysed 29 patients who were treated with prednisolone, including nephrotic syndrome(13 cases). Acute leukemia (10 cases), bronchial asthma(2 cases), juvenile rheumatoid arthritis(2 cases) and ulcerative colitis(1 cases) patients in childhood, after remission induction, prolonged alternate or interrupted treatment was used. The auther observed patterns of height velocity of these patients from 1.6 to 10.3 years. The results were as...
Hypophosphatemic Rickets.
Kyung Mo Kim, Seong Hoon Ha, Dong Kyu Jin, Kwang Wook Ko
Clin Exp Pediatr. 1990;33(4):437-447.   Published online April 30, 1990
Seventeen patients who were diagnosed as primary hypophosphatemic rickets at Department of Pediatrics, Seoul National University Children’s Hospital were analyzed to assess its clinical aspect and effect of treatment, especially on height and growth velosity. The average age of onset was 2 years, and their chief complaints were bowleg and short stature. Sex ratio was l.l:l(male: female). Familial hypophoshatemic rickets was known as X-linked...
A Study on Clinical Course Prognosis and Therapeutic Effect in Childhood ITP.
Sei Woo Chung, Don Hee Ahn
Clin Exp Pediatr. 1987;30(8):874-881.   Published online August 31, 1987
Clinical observations were made on 55 patients of childhood ITP who were diagnosed at the department of Pediatrics, National Medical Center from January 1977 to April 1986. Boys were 30 cases and girls were 25 cases. The following results were obtained. 1) The highest incidence was seen among the children between three and five years of age and the boys were affected more frequently than girls...
Chlorambucil Treatment in Chidren with Frequently Relapsing Minimal Lesion Nephrotic Syndrome.
Myung Hee Chung, Hae Woon Chang, Haeng Mi Kim, Ja Hoo Koo
Clin Exp Pediatr. 1987;30(4):370-377.   Published online April 30, 1987
A clinical study was conducted on children with frequently relapsing nephrotic syndrome to see the therapeutic effectiveness of chlorambucil therapy. Study population consisted of 21 children with biopsy-proven minimal lesion nephrotic syndrome, in whom chlorambucil therapy was given to control their frequent relapses and/or steroid dependency. Eleven patients were frequent relapser and 10 were steroid dependant. Study period extended from December 1980 to August...
Results of Treatment in Children with Acute Lymphocytic Leukemia.
Saeng Gu Cho, Tai Ju Hwang
Clin Exp Pediatr. 1986;29(12):1343-1351.   Published online December 31, 1986
The clinical findings on the 1st examination in 70 patients who were admitted to the pediatric department of Chonnam University Hospital from January, 1977 to January, 1985 as well as the results of treatment in 32 patients were analyzed. The most frequent age at onset was 4-5 years(15 patients). Male patients outnumbered female patients by 1.6 : 1. A mediastinal mass and...
Case Report
A case of Lupus Nephritis.
Kang Hyun Cho, Hae Ok Kim, Don Hee Ahn, Keun Chan Sohn
Clin Exp Pediatr. 1982;25(3):289-294.   Published online March 31, 1982
Lupus nephritis is one of major complications of systemic lupus erythematosus, which determine the outcome of the disease. A case of lupus nephritis was admitted to our pediatric department and renal biopsy was done, which reveraled membranophroliferative type in electron-microscopy. He was treated with prednisone only and responded well in urinary findings. Now, he is maintained with low dose prednisone.
Original Article
Selective Protein Index and Response to Treatment in the Childhood Nephrotic Syndrome.
Chang Ho Hong, Chul Lee, Pyung Kill Kim, Duk Jin Yun
Clin Exp Pediatr. 1981;24(7):645-651.   Published online July 15, 1981
In a group of 59 children with nephrotic syndrome who had been admitted to Severance Ho-spital, during the period of 2 years from July of 1978 till June of 1980, the histological picture seen on renal biopsy, the selective protein index, and the response to the steroid therapy were studied. The degree of selective protein index is not related to...
Review Article
The change of perspective on brain death, euthanasia and withdrawal of the life supporting medical treatments in Korea for pediatric patients
Ivo Kwon
Clin Exp Pediatr. 2009;52(8):843-850.
A recent High Court's decision regarding the withdrawal of life supporting medical treatment (artificial ventilator) from an elderly female patient in the terminal stage has opened up a new era of the "euthanasia dispute" in Korea. With this decision, the legitimate withdrawal of life supporting treatment became possible under certain conditions and the Korean Medical Association is working toward the establishment of practical...
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